Fig. 4

Predicted CD8⁺ T cell epitopes in the P. falciparum circumsporozoite protein (PfCSP). Protein domain information based on the 3D7 reference sequence of PfCSP is found in the first track. The second track are previously experimentally validated (Exp. Val.) epitopes (from [59], after removing duplicate epitope sequences and epitopes > 20 amino acids in length) and the following tracks are epitopes predicted in the PfCSP sequences of NF54, 7G8, NF166.C8, and NF135.C10, respectively. Each box is a sequence that was identified as an epitope, and colors represent the HLA type that identified the epitope. The experimentally validated epitopes do not have HLA types reflected and are simply jittered across two rows