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Fig. 1 | Genome Medicine

Fig. 1

From: Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor

Fig. 1

Loss of heterozygosity and copy-number profiles for PANET samples. Loss of heterozygosity profiles depicted as being copy-loss/haploid (blue), copy-neutral/diploid (purple), or copy-gain/triploid+ (red) for each PANET sample in the a exome, b whole-genome, and c AACR GENIE cohorts. Motif plots describe the most recurrent zygosity (d) or copy-number (eg) states for each chromosome. MAD+ PANETs in the exome and whole-genome cohorts depict patterns of copy-neutral and copy-gain (e), while PANETs in the AACR GENIE cohort depict patterns of copy-loss and copy-gain for MAD+ samples (f) and copy-neutral for MAD− samples (g)

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