Fig. 6
From: Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues
Endogenous retroelements retained sequence homology with viruses. a Barplot showing the frequencies of each amino acid in ereMAPs, viral MAPs, and human canonical MAPs. Abbreviations for amino acids: Y, tyrosine; W, tryptophan; V, valine; T, threonine; S, serine; R, arginine; Q, glutamine; P, proline; N, asparagine; M, methionine; L, leucine; K, lysine; I, isoleucine; H, histidine; G, glycine; F, phenylalanine; E, glutamic acid; D, aspartic acid; C, cysteine; A, alanine. b Human canonical MAPs and ereMAPs were aligned to a database of viral peptides using BLAST, and the percentage of identity of their sequences with viral peptides was computed. The red line represents the average percentage of identity of ereMAPs with viral MAPs. A bootstrap procedure was used to calculate the percentage of identity of 10,000 sets of 103 randomly selected human canonical MAPs with viral MAPs. P value was calculated as the number of times the bootstrap distribution had a higher percentage of identity with viral MAPs than ereMAPs (P < 0.0001)