Table 5 Cox proportional hazards regression for high-TMB patients in combined melanoma cohorts
From: MHC-I genotype and tumor mutational burden predict response to immunotherapy
Variables | Coefficients | P value | Confidence interval (95%) |
|---|---|---|---|
Age | OS − 0.01 | OS 0.59 | OS (− 0.04, 0.02) |
PFS 0.06 | PFS 0.13 | PFS (− 0.02, 0.15) | |
Sex | OS − 0.33 | OS 0.40 | OS (− 1.09, 0.44) |
PFS − 0.10 | PFS 0.90 | PFS (−1.67, 1.47) | |
TMB | OS − 0.03 | OS 0.05 | OS (− 0.05, 0.00) |
PFS 0.03 | PFS 0.24 | PFS (− 0.02, 0.07) | |
min-PHBR | OS 0.28 | OS 0.03* | OS (0.02, 0.54) |
PFS 0.82 | PFS 0.02* | PFS (0.15, 1.49) |