Skip to main content

Table 5 Cox proportional hazards regression for high-TMB patients in combined melanoma cohorts

From: MHC-I genotype and tumor mutational burden predict response to immunotherapy

Variables Coefficients P value Confidence interval (95%)
Age OS − 0.01 OS 0.59 OS (− 0.04, 0.02)
PFS 0.06 PFS 0.13 PFS (− 0.02, 0.15)
Sex OS − 0.33 OS 0.40 OS (− 1.09, 0.44)
PFS − 0.10 PFS 0.90 PFS (−1.67, 1.47)
TMB OS − 0.03 OS 0.05 OS (− 0.05, 0.00)
PFS 0.03 PFS 0.24 PFS (− 0.02, 0.07)
min-PHBR OS 0.28 OS 0.03* OS (0.02, 0.54)
PFS 0.82 PFS 0.02* PFS (0.15, 1.49)