Fig. 2
From: Modeling and analysis of Hi-C data by HiSIF identifies characteristic promoter-distal loops
Performance of FTR and FDR of HiSIF. a The number of SIFs at various FTR thresholds. The number of SIFs decreased rapidly along with increasing FTR threshold. b The number of SIFs at various FDRs. It was clear that most SIFs detected by HiSIF were at FDR less than 0.25. c, d The number of SIFs with various sequence depths in GM12878 and hESC cells. The number of SIFs increased rapidly along with increasing sequence depth. However, for a given sequence depth, SIFs detected in hESC Hi-C data (HindIII) were nearly an order of magnitude higher than those detected in GM12878 in situ Hi-C data (MboI)