Fig. 4

Correlation of DNA methylation and gene expression of DMPs situated in gene promoters/TSS. a Percentage of detected short-range interactions that present either negative or position correlation between DNA methylation and gene expression, in which the DMP is situated in promoter or TSS of interacting DEG. b GO analysis utilizing the DAVID online tool of the DEGs with short-range interacting DMPs. c Graphical representation of correlation of DNA methylation and gene expression of DMP-DEG pairs. Red and blue dots represent SSc and HD individuals, respectively