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Fig. 3 | Genome Medicine

Fig. 3

From: Characterization of the dual functional effects of heat shock proteins (HSPs) in cancer hallmarks to aid development of HSP inhibitors

Fig. 3

Dual functional effects of HSPs in cell proliferation. a Correlation between HSPs and proliferation marker (ki67) across cancer types. Histogram height denotes number of cancer types with significant correlation between ki67 and HSPs. Red and blue colored squares denote positive and negative correlation. Colored bar on bottom denotes HSP families. b Correlation between HSPs and ki67 across ~ 1000 cancer cell lines. c Significant decrease in proliferation score in cancer cell lines by knocking out individual HSPs from Project Achilles. Gray box denotes the average proliferation score of all genes tested

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Genome Medicine

ISSN: 1756-994X

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