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Fig. 2 | Genome Medicine

Fig. 2

From: Comprehensive molecular characterization of gastric cancer patients from phase II second-line ramucirumab plus paclitaxel therapy trial

Fig. 2

Ramucirumab response based on molecular classification. a Percentage of GC patients with clinical response based on TCGA (left panel) and ACRG (right panel) classification. b Box plots demonstrating pathway enrichment scores of each corresponding pathway. Box plots span from the first to third quantiles, and the whiskers represent the 1.5 interquartile range. c Genomic landscape of gastric patients focusing on RTK-RAS, PI3K, and DDR encoding genes. Genomic amplifications are highlighted in red and mutations are highlighted in green. Patients are ordered based on TCGA molecular classification. P values in a were derived from chi-squared tests, and the P values in b were derived from one-way ANOVA

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