Table 1 Characteristics of BioMe participants eligible to receive results and receiving results through a pilot genomic screening program
Participant demographics and characteristics | Eligible to receive results (N = 692) | Received P/LP results | Downgraded variants (N = 12) | ||
|---|---|---|---|---|---|
CDC tier 1 (N = 40) | hATTR (N = 34) | CDC tier 1 + hATTR (N = 74) | |||
Age, median (range) | 60 (18–95) | 61 (28–83) | 57 (30–80) | 58 (28–83) | 61 (30–76) |
Female sex, N (%) | 458 (66.2) | 33 (82.5) | 28 (82.4) | 61 (82.4) | 8 (66.7) |
Self-reported race/ethnicity, N (%) | |||||
 African American/African | 156 (22.5) | 6 (15.0) | 18 (52.9) | 24 (32.4) | 3 (25.0) |
 East/Southeast Asian | 26 (3.8) | 2 (5.0) | 0 | 2 (2.7) | 3 (25.0) |
 European | 186 (26.9) | 20 (50.0) | 1 (2.9) | 21 (28.4) | 5 (41.7) |
 Hispanic/Latinx | 249 (36.0) | 8 (20.0) | 15 (44.1) | 23 (31.1) | 0 |
 Native American | 1 (0.1) | 0 | 0 | 0 | 0 |
 Other | 41 (5.9) | 3 (7.5) | 0 | 3 (4.1) | 1 (8.3) |
 South Asian | 9 (1.3) | 0 | 0 | 0 | 0 |
 Multiple selected | 22 (3.2) | 1 (2.5) | 0 | 1 (1.4) | 0 |
 Not available | 2 (0.3) | 0 | 0 | 0 | 0 |
Spanish as preferred language, N (%) | – | 0 | 3 (8.8) | 3 (4.1) | – |
Prior knowledge of genomic risk, N (%) | – | 14 (35.0) | 1 (2.9) | 15 (20.3) | – |
Mode of result disclosure, N (%) | – |  |  |  | – |
 In-person |  | 24 (60.0) | 26 (76.5) | 50 (67.6) |  |
 Telemedicine |  | 16 (40.0) | 8 (23.5) | 24 (32.4) |  |