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Fig. 3 | Genome Medicine

Fig. 3

From: Noninvasive prenatal testing of α-thalassemia and β-thalassemia through population-based parental haplotyping

Fig. 3

Effect of the reference panel sample size on the outcomes of PBH-NIPT. We randomly extracted one-half, one-quarter, one-sixth, one-eighth, one-twelfth, and 50 of the samples from the total reference panel and performed three independent tests for a β-thalassemia and b α-thalassemia. In the 52 fetuses in whom NIPT successfully inferred both alleles, the outcome of NIPT improved as the sample size of the reference panel increased

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Genome Medicine

ISSN: 1756-994X

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