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Table 2 Differentially abundant OTUs between NG and PD subjects from both Danish and Indian cohorts

From: Trans-ethnic gut microbial signatures of prediabetic subjects from India and Denmark

OTU IDs

Taxonomic affiliation

Log2 fold change

Log2 FC standard error

BH-adjusted p value

Mean % abundance

Enriched in NG

 291725

Prevotella_9

− 1.7680

0.5088

8.88E−03

0.2918

 556835

Phascolarctobacterium faecium

− 1.5371

0.4627

1.38E−02

0.2914

 190975

Barnesiella intestinihominis

− 1.6235

0.4381

4.56E−03

0.0567

 335550

Flavonifractor plautii

− 1.1188

0.3509

1.86E−02

0.0457

 4315782

[Family]Ruminococcaceae

− 2.4732

0.7731

1.83E−02

0.0147

 659361

Tyzzerella_4 nexilis

− 2.4165

0.8183

3.45E−02

0.0097

 583656

Bacteroides nordii

− 1.7518

0.3759

1.97E−04

0.0092

 583256

Faecalibacterium

− 1.7176

0.2714

5.54E−08

0.0087

 211935

Agathobacter

− 1.0416

0.3203

1.66E−02

0.0086

 177679

[Family]Muribaculaceae

− 1.4553

0.4535

1.79E−02

0.0048

 819181

Ruminococcaceae_UCG-002

− 1.0428

0.3378

2.38E−02

0.0033

 593008

Christensenellaceae_R-7_group

− 1.7182

0.5400

1.88E−02

0.0033

 denovo32180

Ruminococcaceae_UCG-010

− 2.0100

0.7128

4.73E−02

0.0030

Enriched in PD

 817140

Megasphaera elsdenii

1.7989

0.3362

1.12E−05

1.1755

 349024

Streptococcus equinus/gallolyticus/infantarius/lutetiensis

2.0231

0.3458

7.59E−07

0.8744

 339221

Prevotella_9

1.4210

0.3933

6.20E−03

0.8176

 357046

Alistipes finegoldii/onderdonkii

1.3202

0.3080

8.10E−04

0.4661

 13811

Mitsuokella

1.3869

0.3688

4.05E−03

0.3890

 1111294

Escherichia/Shigella albertii/ boydii/coli/dysenteriae/fergusonii/flexneri/sonnei/vulneris

2.0982

0.3131

6.45E−09

0.3829

 264967

Megasphaera

1.9031

0.3591

1.21E−05

0.3539

 566899

[Family]Ruminococcaceae

1.0812

0.3529

2.50E−02

0.3489

 269937

Prevotella_2

2.5823

0.5627

2.47E−04

0.2158

 345899

Prevotella_9

1.5634

0.4830

1.69E−02

0.1898

 1767788

Vibrio cholerae

3.3938

0.6447

1.37E−05

0.1604

 denovo49732

Lactobacillus

1.1079

0.3289

1.21E−02

0.1374

 546557

Alloprevotella

2.5351

0.5821

6.27E−04

0.1229

 278795

Rhodococcus baikonurensis/ boritolerans/degradans/ erythropolis/globerulus/hoagii/ opacus/qingshengii/rhodochrous

1.1766

0.2996

2.43E−03

0.1102

 211191

[Family]Ruminococcaceae

1.0446

0.3314

1.99E−02

0.1033

  1. Differentially abundant OTUs between NG and PD subjects, belonging to the Indian and Danish cohorts (pooled together), identified using a negative binomial Wald test (corrected for geography-specific cohort effect). A positive log2 fold change value indicates higher relative abundance of the OTU in PD subjects and vice versa. P values were adjusted for multiple testing using Benjamini-Hochberg correction. Up to top 15 OTUs (sorted according to mean abundance values) which are at least twofold enriched (padj < 0.05) either in the NG or the PD group are listed
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Genome Medicine

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