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Fig. 1 | Genome Medicine

Fig. 1

From: Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Fig. 1

Mutational load in breast cancer primary tumors and their metastatic counterparts by whole-exome sequencing. a Average mutation rate in primary tumors (PT) and their matched metastatic tissue (M). b Average mutation rate in primary tumors (PT) and their matched metastatic tissue (M), according to the subtype of the primary tumor. The mutational burden in all paired samples (a) and by molecular subtypes (b) is represented as the number of mutations per megabase of sequence. The violin plots represent the distribution of the data. Asterisks indicate a statistically significant difference among TNBC and luminal B patients (Wilcoxon rank-sum test false discovery rate)

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Genome Medicine

ISSN: 1756-994X

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