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Table 1 Population characteristics at the primary tumor and metastatic settings

From: Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

    Patients
N %
PT Tumor size pT0, pT1 39 38
≥ pT2 61 60
pTx 2 2
NA 1 1
No surgery for PT   20 16
Node invasion* pN0 38 36
pN+ 65 64
Histo-prognostic grade* 1 12 10
2 45 37
3 63 51
NA 3 2
PT treatment Neo adjuvant chemotherapy 42 34
Adjuvant chemotherapy 56 46
Adjuvant endocrine therapy 65 53
Adjuvant anti HER2 therapy 14 11
M Age median (min-max), years 57 (28–81)
Time PT-M median (min-max), months 42 (0–270)
M onset De novo M 23 19
Late M 100 81
Number of M sites 1 metastatic site 48 39
> 1 metastatic site 75 61
M sites Liver 74 60
Bone 53 43
Lymph node 54 44
Lung/pleura 42 34
Skin 9 7
CNS 6 5
Ovary 3 2
  1. PT primary tumor, M metastases, CNS central nervous system