Table 1 Population characteristics at the primary tumor and metastatic settings

PT

Tumor size

pT0, pT1

39

38

≥ pT2

61

60

pTx

2

2

NA

1

1

No surgery for PT

20

16

Node invasion*

pN0

38

36

pN+

65

64

Histo-prognostic grade*

1

12

10

2

45

37

3

63

51

NA

3

2

PT treatment

Neo adjuvant chemotherapy

42

34

Adjuvant chemotherapy

56

46

Adjuvant endocrine therapy

65

53

Adjuvant anti HER2 therapy

14

11

M

Age

median (min-max), years

57

(28–81)

Time PT-M

median (min-max), months

42

(0–270)

M onset

De novo M

23

19

Late M

100

81

Number of M sites

1 metastatic site

48

39

> 1 metastatic site

75

61

M sites

Liver

74

60

Bone

53

43

Lymph node

54

44

Lung/pleura

42

34

Skin

9

7

CNS

6

5

Ovary

3

2