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Fig. 3 | Genome Medicine

Fig. 3

From: Profiling SARS-CoV-2 mutation fingerprints that range from the viral pangenome to individual infection quasispecies

Fig. 3

Individual and joint frequencies of mutations in 75,681 SARS-CoV-2 genomes. a Mutations occurring in at least 100 of the 75,681 SARS-CoV-2 genomes, with top 5 most frequent mutations annotated. Colors indicate the variant allele (see legend). b Top 20 most frequent co-occurring sets of mutations (“fingerprints”) among 75,681 GISAID genomes. Each gray rectangle corresponds to one fingerprint, with vertical line segments located at the positions of the variants in that fingerprint, and with line segment colors indicating the variant alleles (see legend). The height of each rectangle is equal to the number of GISAID genomes with the associated fingerprint, so the single most frequent fingerprint is the bottommost rectangle. The 4th most frequent fingerprint (4th rectangle from the bottom) has no variants relative to the SARS-CoV-2 reference genome

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Genome Medicine

ISSN: 1756-994X

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