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Fig. 2 | Genome Medicine

Fig. 2

From: Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers

Fig. 2

AMR gene abundance and α-diversity increases with travel and AMR gene β-diversity decreases. a The left panel shows the AMR gene abundance in RPKM. Each point is a sample, and the boxes are the medians with interquartile ranges for the pre-travel samples in blue and the post-travel samples in red. The p value (paired-sample t test) for the comparison is given at the top of the panel. The right panel shows the difference between the bootstrapped distributions of the post- and pre-travel samples. The red line gives the 95% confidence interval for the difference, and the point gives the estimate. b AMR gene α-diversity is measured by richness (top left panel), and Shannon Index (bottom left panel) is compared between the pre-travel (blue) and post-travel (red) samples. Each point corresponds to a given sample, and each box gives the median and interquartile range for the distribution. The p value (paired-sample t test) for the comparison is given at the top of each panel. The panels to the right of the boxplots show the difference between the bootstrapped distributions of the post- and pre-travel samples. The red line gives the 95% confidence interval for the difference and the point gives the estimate. c AMR gene β-diversity measured by Bray-Curtis dissimilarity is compared between the pre-travel (blue) and post-travel (red) samples. Each point is a comparison between two samples within the same time point group. The distributions are shown to the right of the points, and boxplots showing the median and interquartile ranges are overlaid on top of the points. The p value by paired Wilcoxon test for the comparison is shown near the top. In the right panel, the lines show the 95% confidence intervals, and points show the mean values for the pre- (blue) and post-travel (red) Bray-Curtis dissimilarity distributions. Source data is provided in the source data file (Additional file 3)

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