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Fig. 3 | Genome Medicine

Fig. 3

From: Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial

Fig. 3

“Matched therapies:” list of AGAs and therapeutic responses. a AGAs targeted by “matched therapies.” Seven patients with mutations in homologous recombination (HR) DNA repair-related genes displayed also high HRD score (BRCA1: 1; BRCA2: 3; RAD51B: 2; RAD51D: 1). b Objective responses to “matched therapies” displayed as alluvial plots. Left: therapies ordered by drug classes. Middle: responses ordered from CR to PD. CR = complete responses, PR = partial responses; SD = stable disease, and PD = progressive disease. Right: cancer types alphabetically ordered

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Genome Medicine

ISSN: 1756-994X

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