Skip to main content
Fig. 5 | Genome Medicine

Fig. 5

From: scGRNom: a computational pipeline of integrative multi-omics analyses for predicting cell-type disease genes and regulatory networks

Fig. 5

Cross-cell-type conserved and cell-type-specific functions, pathways, and protein-protein interactions in schizophrenia and Alzheimer’s disease. Darkness in heatmaps is proportional to −log10(p) of the enrichment. a The enrichments of select conserved and specific functions/pathways (e.g., GO, KEGG, REACTOME) across cell-type disease genes in schizophrenia. b The enrichments of protein-protein interactions among major cell-type disease genes in schizophrenia: excitatory neuron (broad, red), inhibitory neuron (broad, blue), microglia (green), and oligodendrocyte (purple). c The enrichments of select conserved and specific functions/pathways across cell-type disease genes in Alzheimer’s disease. d The enrichments of select conserved and specific functions/pathways across cell-type disease genes between schizophrenia and Alzheimer’s disease

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us