Fig. 5

A Differentially abundant genera between baseline and 3 months (blue bars) and baseline and 1 year (red) within the complete cohort with available taxonomy at all timepoints (n = 48). Differential abundance is calculated on ASV level abundances using taxonomy after stringent control for contamination at a decontam score 0.5 and reported at the genus level. Only significant differential abundances (Padj < 0.01) are reported. B Differentially abundant genera in subjects with T2D, who experienced T2D remission as compared to those with persistent T2D (n = 12 in both groups). Color shading represents p-values. C Differentially abundant genera in good responders vs poor responders (n = 24 vs 13 respectively). Color shading represents p-values. D Spearman’s rank correlations of differentially abundant genera in good responders and subjects with T2D remission with host variables in all timepoints. (+) indicates a significance level < 0.05