Table 1 Baseline cohort characteristics of subjects with complete follow-up

N

24

24

 Sex (F/M)

18/6

17/7

1

 Age (years)

46.8 ± 8.59

50.1 ± 7.94

0.007

 BMI (kg/m²)

50.8 ± 6.59

49.0 ± 6.68

0.943

 WHR

0.91 [0.87; 0.95]

0.98 [0.99; 1.03]

0.006

 GFR (ml/min/1.73m²)

93.8 [80.6; 114]

94.0 [79.6; 110]

0.996

  Active smokers, N (%)

2 (8.70%)

3 (12.5%)

1

 HbA1c (%)

5.38 [5.29; 5.58]

6.56 [5.95; 8.22]

< 0.001

 FPG (mmol/l)

5.25 [4.98; 5.42]

7.42 [6.54; 11.7]

< 0.001

 HOMA-IR

3.10 [2.27; 4.53]

8.59 [5.71; 13.8]

< 0.001

 Nr antidiabetics

0.00 [0.00; 0.00]

1.00 [1.00; 3.00]

< 0.001

 Hypertension, N (%)

16 (66.7%)

22 (91.7%)

0.076

 Number of anti-HTN drugs, N

1.00 [1.00; 3.00]

3.50 [1.00; 5.00]

0.067

 Systolic blood pressure (mmHg)

131 ± 11.0

133 ± 14.7

0.665

 Diastolic blood pressure (mmHg)

76.8 ± 8.26

76.4 ± 15.1

0.924

 LDL-C (mmol/l)

3.25 ± 0.87

3.09 ± 0.93

0.545

 HDL-C (mmol/l)

1.27 [1.02; 1.52]

1.10 [0.94; 1.30]

0.105

 TG (mmol/l)

1.52 (0.69)

1.67 [1.42; 2.24]

0.017

 Statin, N (%)

1 (4.17%)

7 (29.2%)

0.048

 Ezetimib, N (%)

0.00 (0.00%)

2 (8.33%)

0.489

 Hemoglobin (g/dl)

13.4 [13.0; 14.5]

14.2 [13.4; 14.9]

0.115

 Leukocytes (Gpt/l)

6.70 [5.25; 7.20]

8.30 [7.65; 10.7]

< 0.001

 CRP (pg/ml)

10.4 [3.47; 17.9]

8.72 [5.24; 22.8]

0.546