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Fig. 1 | Genome Medicine

Fig. 1

From: Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma

Fig. 1

Local PPI network representing the druggable proteins for non-WNT MB. CIS-derived candidate cancer genes are represented by large circles, whilst small circles represent the proteins that interact with these CIS-derived candidates. Nodes coloured in red–light red represent significantly over-expressed proteins in Gp3 MB, whilst blue–light blue nodes represent significantly under-expressed proteins in Gp3 MB. White small diamond shaped nodes represent drugs for that protein. For expression data for each node in the network, see Additional file 4

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