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Fig. 7 | Genome Medicine

Fig. 7

From: High-grade serous tubo-ovarian cancer refined with single-cell RNA sequencing: specific cell subtypes influence survival and determine molecular subtype classification

Fig. 7

Subclustering of endothelial cells. A, B t-SNE plots showing colour-coded the annotated endothelial cell subclusters (A) as well as the distribution of the endothelial cells across patients, the different sampling sites (ovary, omentum, peritoneum) and type of tissue (tumour vs non-tumour) (B). C t-SNE plots illustrating the gene expression of lymphatic endothelial cells (PROX1, LYVE1, CCL21, VEGFR3). D, E Heatmap of active metabolic pathways (D) and transcription factor activity (E) in endothelial cell subclusters

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