Fig. 3

Aggregate comparison for select primary tumor types. A, B Principal component analysis for liver and bile duct tissues based on codon usage (A) and codon pair usage (B). C, D Euclidean distance dendrogram for liver and bile duct tissues based on codon usage (C) and codon pair usage (D). E, F Principal component analysis for colorectal tissues based on codon usage (E) and codon pair usage (F). “Right” colon refers to the ascending colon, cecum, and hepatic flexure of the colon. “Left” colon refers to the descending colon, splenic flexure of the colon, sigmoid colon, rectosigmoid junction, and rectum. G, H Euclidean distance dendrograms for colorectal tissues based on codon usage (G) and codon pair usage (H). I, J Principal component analysis for gastric and esophageal tissues based on codon (I) and codon pair usage (J). K, L Euclidean distance dendrograms for gastric and esophageal tissues based on codon (K) and codon pair usage (L)