Fig. 5

Codon and codon pair usage differences in prostate adenocarcinoma patients. A–D Representative scatterplots for 4 prostate adenocarcinoma patients. Case numbers are assigned in order of decreasing MSE (case 1 refers to the patient with the highest MSE while case 50 refers to the patient with the lowest MSE). E, G PCA based on codon usage in each patient’s normal prostate tissue (E) or primary tumor tissue (G). Cases with high MSE are colored red, and cases with low MSE are colored blue. F, H PCA based on codon pair usage in each patient’s normal prostate tissue (F) or primary tumor tissue (H). Cases with high MSE (> 16) are colored red, and cases with low MSE (< 3) are colored blue