Fig. 5
Comparison between in vitro and in vivo snRNA-seq datasets. A Intersection of the total number of detected genes in the snRNA-seq dataset of cultured human islets (in vitro snRNA-seq, green circle) and the snRNA-seq dataset of transplanted human islets (in vivo snRNA-seq, yellow circle). B–D Scatter plots of harmonized cell type-specific gene expression in B α-cells, C β-cells, D PP-cells, and E δ-cells between the in vitro and the in vivo snRNA-seq datasets. X-axis and Y-axis represent the gene expression levels expressed as natural log of counts in the indicated datasets. The blue line in each plot represents the regression line, whose fit is indicated by the R2 value (the square of the Pearson correlation coefficient). The P and R values are provided for each correlation