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Fig. 3 | Genome Medicine

Fig. 3

From: Recombination and lineage-specific mutations linked to the emergence of SARS-CoV-2

Fig. 3

Tracing the evolution of RBD in Sarbecoviruses. a Tanglegram displaying the differences between the trees derived from the RBD recombination segment and that from the rest of the genome. Sequence names were colored according to the host they were sampled from. Circles represent Shimodaira-Hasegawa-like supports higher than 0.80. b Track of the evolutionary changes that occurred in the RBD from human-infecting Sarbecoviruses and their closest relatives. The ancestral reconstruction analyses were performed using the maximum likelihood phylogenetic tree derived from RBD recombination event as input. Black circles in the ML tree represent nodes with Shimodaira-Hasegawa-like support higher than 0.80

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