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Table 1 Clinicopathological characteristics of patients with resected CRLM in the in-house series

From: De novo transcriptomic subtyping of colorectal cancer liver metastases in the context of tumor heterogeneity

Clinicopathological variable Patients (total n = 171) %
Gender, male 106 62
Primary tumor location   
  Proximal colon 36 21
  Distal colon 135 79
Primary tumor differentiation (unknown, n = 19)   
  Well 25 15
  Moderate 107 63
  Poor 20 12
Nodal status primary tumor (unknown, n = 8)   
  N0 50 29
  N1 62 36
  N2 51 30
Synchronous (within 6 months) liver metastasis 133 78
Previous resection/radiofrequency ablation of CRLM 39 23
Systemic oncological treatment prior to tumor sampling 156 91
  Neoadjuvant chemotherapy for this metastatic situation 131 77
  Previous chemotherapy before this metastatic situation 52 30
  Molecularly targeted treatment, previous or neoadjuvant 51 30
Radiofrequency ablation 22 13
R-status liver   
  R0-resection 71 42
  R1-resectiona 91 53
  R2-resectionb 9 5
Extra-hepatic disease 40 23
Multiple CRLM analyzed (patients, tumors, samples) 47/141/158  
  1. a1 mm resectional margin or lesions treated with radiofrequency ablation
  2. b Macroscopic residual tumor in liver (visible at surgery or by radiological examination)