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Table 2 Patient characteristics contributing to the variance in gut microbial community composition

From: Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis

Patient characteristicsφ

Marginal model

Adjusted model

Variance (%)

P value#

Variance (%)

P value#

Age group

7.7

0.001

7.7

0.001

MCII patient group

4.4

0.003

3.8

0.002

csDMARDs

3.7

0.008

3.1

0.008

Sex

3.1

0.024

2.9

0.013

Smoking status

4.0

0.009

2.7

0.028

CDAI

2.3

0.120

2.3

0.056

bDMARDs

1.8

0.324

1.6

0.280

Prednisone

1.7

0.350

1.6

0.284

  1. φEach patient characteristic was measured for 32 patients at both clinical visits. All 64 gut microbiome samples were analyzed simultaneously using Permutational Multivariate Analysis of Variance (PERMANOVA); #PERMANOVA was used to test for statistical association between corresponding patient characteristic and variance within microbiome composition
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Genome Medicine

ISSN: 1756-994X

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