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Fig. 4 | Genome Medicine

Fig. 4

From: Constructing germline research cohorts from the discarded reads of clinical tumor sequences

Fig. 4

Polygenic risk score (PRS) accuracy. a Scatter plot of germline SNP (x-axis) and tumor imputed (y-axis) polygenic risk score across individuals. Each dot is an individual; dashed line shows y = x diagonal; blue line shows the linear fit. b Violin plot of imputed score density (y-axis) as a function of genotyped score decile (x-axis). c Violin plot of the density of imputed/genotyped score differences (x-axis) across cancer types (y-axis)

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