Table 2 Summary of demographic information and clinical parameters of the independent prospective Colombia cohort. For days from sample to severe dengue (SD) onset, “0” indicates patients whose sample was collected on the day of (at least several hours prior to) the appearance of SD manifestations. WS, warning signs; NS1 Ag, nonstructural protein 1 antigen; DENV, dengue virus
From: An 8-gene machine learning model improves clinical prediction of severe dengue progression
Dengue (N=93) | Dengue with WS (N=262) | Severe dengue (N=22) | ||
|---|---|---|---|---|
Age | Adult | 39 | 86 | 13 |
Child (<17 years) | 54 | 176 | 9 | |
Gender | Male | 49 | 137 | 6 |
Female | 44 | 125 | 16 | |
Total | 93 | 262 | 22 | |
First sample day | Mean (range) | 5.0 (1–10) | 5.2 (0–10) | 4.8 (0–7) |
Days from sample to SD onset | Median (range) | - | - | − 1 (− 3, 0) |
Dengue diagnostics | Positive NS1 Ag | 60 | 215 | 17 |
Positive DENV IgM | 53 | 149 | 9 | |
Dengue exposure | Primary | 29 | 59 | 5 |
Secondary | 59 | 186 | 15 | |
Undetermined | 5 | 17 | 2 | |
Dengue serotype | DENV-1 | 40 | 135 | 10 |
DENV-2 | - | 3 | - | |
DENV-3 | 1 | 3 | 3 | |
DENV-4 | 2 | 3 | 1 | |
DENV co-infected | - | 1 | - | |
Unknown | 50 | 117 | 8 |