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Table 2 Summary of demographic information and clinical parameters of the independent prospective Colombia cohort. For days from sample to severe dengue (SD) onset, “0” indicates patients whose sample was collected on the day of (at least several hours prior to) the appearance of SD manifestations. WS, warning signs; NS1 Ag, nonstructural protein 1 antigen; DENV, dengue virus

From: An 8-gene machine learning model improves clinical prediction of severe dengue progression

   Dengue (N=93) Dengue with WS (N=262) Severe dengue (N=22)
Age Adult 39 86 13
Child (<17 years) 54 176 9
Gender Male 49 137 6
Female 44 125 16
Total   93 262 22
First sample day Mean (range) 5.0 (1–10) 5.2 (0–10) 4.8 (0–7)
Days from sample to SD onset Median (range) - - − 1 (− 3, 0)
Dengue diagnostics Positive NS1 Ag 60 215 17
Positive DENV IgM 53 149 9
Dengue exposure Primary 29 59 5
Secondary 59 186 15
Undetermined 5 17 2
Dengue serotype DENV-1 40 135 10
DENV-2 - 3 -
DENV-3 1 3 3
DENV-4 2 3 1
DENV co-infected - 1 -
Unknown 50 117 8