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Table 1 Demographic characteristics, anthropometric and metabolic measurements of the study participants pre- and post-LED

From: Gut microbiota predicts body fat change following a low-energy diet: a PREVIEW intervention study

Characteristic

pre-LED

post-LED

P value*

Demographic variables

 No. of participants

211

–

–

 Female, No. (%)

156 (74)

–

–

Age (years), mean (95% CI)

54 (53–55)

–

–

Ethnicity, No. (%)

 Caucasian

194 (92)

–

–

 Polynesian

13 (6)

–

–

 Asian

3 (1)

–

–

 Other

1 (0.4)

–

–

Anthropometric variables

 BMI (kg/m2), mean (95% CI)

34.1 (33.3–34.9)

30.2 (29.5–30.9)

<0.001

 Body weight (kg), mean (95% CI)

95.8 (93.3–98.2)

84.7 (82.5–86.9)

<0.001

 Waist circumference (cm), mean (95% CI)

108.6 (106.9–110.2)

98.4. (96.8–100.0)

<0.001

Body composition

 Body fat mass (kg), mean (95% CI)

40.1 (38.3–41.8)

31.8 (30.2–33.5)

<0.001

 Body fat (%), mean (95% CI)

41.8 (407–42.9)

37.3 (36.0–38.6)

<0.001

 Fat-free mass (kg), mean (95% CI)

55.6 (54.1–57.1)

52.9 (51.5–54.3)

<0.001

Metabolic variables

 Insulin (mU/L), mean (95% CI)

13.1 (12.1–14.0)

7.9 (7.4–8.4)

<0.001

 FPG (mmol/L), mean (95% CI)

6.2 (6.2–6.3)

5.8 (5.7–5.9)

<0.001

 HOMA-IR, mean (95% CI)

3.6 (3.4–3.9)

2.0 (1.9–2.2)

<0.001

 HbA1c (mmol/mol), mean (95% CI)

37.0 (36.6–37.5)

34.8 (34.3–35.2)

<0.001

 C-peptide (pmol/L), mean (95% CI)

908.3 (867.2–949.3)

648.0 (616.9–679.1)

<0.001

  1. FPG fasting plasma glucose, HOMA-IR homeostasis model assessment of insulin resistance
  2. *P value pre-LED vs post-LED was calculated using paired t-test for FPG and body fat % and Wilcoxon signed-rank test for other variables