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Fig. 2 | Genome Medicine

Fig. 2

From: Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants

Fig. 2

Distribution of the TF binding–disrupting SNPs across the human genome. a The number of SNPs that affect the binding affinity of specific TFs. b Distribution of the TF binding–disrupting SNPs across the human genome. A large proportion of the functional SNPs disrupt the binding of CTCF, and over half of the functional SNPs are located in intronic regions

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Genome Medicine

ISSN: 1756-994X

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