Fig. 2
From: Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes
Candidate genes in genomic regions recurrently affected by focused amplifications or deletions. A GISTIC scores (y-axis) per chromosome (x-axis) for combined dataset of acral and mucosal melanomas. Recurrently (q-values < 0.1) amplified regions are colored red and recurrently deleted regions are colored blue, with relevant oncogenes and tumor suppressors labeled. Putative melanoma driver genes are marked in parentheses. B, C Minimally amplified regions (indicated in vertical lines) for amplifications of chromosome 5 with candidate genes. The filled circles on the left side indicate mucosal melanomas, with unlabeled cases representing acral melanomas. For panel B, the amplified region is shown at two different resolutions