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Fig. 3 | Genome Medicine

Fig. 3

From: Penetrance estimation of Alzheimer disease in SORL1 loss-of-function variant carriers using a family-based strategy and stratification by APOE genotypes

Fig. 3

Number of affected and unaffected individuals according to their age and their SORL1 status after genotyping imputation. This graph was obtained for all individuals with AAO or censoring above 40 years. It represents the number of carriers (upper part) and non-carriers (lower part) of the SORL1-LoF variant according to their disease status and age intervals (AAO for probands and affected relatives and censoring for unaffected relatives). Transparency differentiates available genotypes (already known, including those of probands) from those estimated at the end of the algorithm

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Genome Medicine

ISSN: 1756-994X

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