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Fig. 4 | Genome Medicine

Fig. 4

From: Network reconstruction for trans acting genetic loci using multi-omics data and prior information

Fig. 4

Inferred networks for the schizophrenia susceptibility locus rs9274623 obtained from eQTLgen (A) and the rs9318186 locus obtained from GTEx (B). The white boxes indicate sentinel SNPs, pink ovals indicate SNP-Genes, blue ovals transcription factors, and white ones shortest path-derived genes. Light green ovals represent genes trans-associated to the SNP. Black edges were inferred during network inference. In addition to being inferred, colored edges indicate ChIP-seq protein-DNA binding evidence (green), protein-protein interaction in the BioGrid (purple), and whether or not a gene is encoded in cis of the linked entity (blue)

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