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Fig. 3 | Genome Medicine

Fig. 3

From: Genomic and transcriptomic analysis of a diffuse pleural mesothelioma patient-derived xenograft library

Fig. 3

Gene expression changes in mesothelioma PDX models as a function of histologic subtype. A Sample to sample subtype correlation plot using the top 100 highest variance genes. The spearman correlation was used, and the samples were ordered using hierarchical clustering with complete linkage. B Principal component analysis plot showing mesothelioma PDX samples color-coded based on subtype annotation. C Volcano plot showing top differentially expressed genes (DEGs) in epithelioid vs non-epithelioid subtype comparison D Pathway enrichment analyses on the DEGs of the epithelioid vs non-epithelioid subtype comparison

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Genome Medicine

ISSN: 1756-994X

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