Table 1 Patient demographics at the time of PDX collection
Characteristics | Patient (n = 22) n (%) |
|---|---|
Age, median (range) | 70 (33, 81) |
Sex | |
 Male | 19 (86) |
 Female | 3 (14) |
Smoking status | |
 Current/former | 15 (68) |
 Never | 7 (32) |
Asbestos exposurea | |
 Yes | 14 (63) |
 No | 5 (23) |
 Unknown | 3 (14) |
Histology | |
 Epithelioid | 15 (68) |
 Biphasic | 5 (23) |
 Sarcomatoid | 2 (9) |
Stage at diagnosis | |
 I–IIIA | 14 (64) |
 IIIB–IV | 8 (36) |
Pleurectomy decortication | 10 (45) |
Thoracic radiation | |
 IMRT | 8 (36) |
 Definitive | 2 (9) |
Platinum + pemetrexed +/− VEGF inhibitor PFS (months) | (n = 20) |
 Median (range) | 7.8 (1.2, 25.2) |
  ≤ 6 months | 10 |
  > 6 months | 10 |
Overall survival (months) | |
 Median (range) | 17.4 (6.2, 50.8) |