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Fig. 4 | Genome Medicine

Fig. 4

From: A one-year genomic investigation of Escherichia coli epidemiology and nosocomial spread at a large US healthcare network

Fig. 4

Potential clusters of transmission were defined as groups of isolates from ≥2 patients with ≤17 SNP differences. A Stacked histograms showing the number of MDR and non-MDR cluster isolates according to their ST and B the number of distinct outbreak clusters per ST. Clusters grouping either MDR or non-MDR isolates are shown in red and gray, respectively. Hybrid clusters (i.e., grouping both MDR and non-MDR isolates) are shown in yellow. STs associated with a single cluster were grouped into others and represent ST-244, ST-394, ST-62, ST-372, ST-404, ST-421, ST-428, ST-538, ST-607, ST-1431, ST-1597, and ST-7887. C Analysis of outbreak clusters (identified on the y-axis with the corresponding ST) involving ≥3 patients (n = 24) and ordered temporally. The legend describes novel patients (filled circles), serial isolates (open circles), MDR isolates (red-filled circles), non-MDR (black-filled circles), and outbreaks consisting of all ESBL-E. coli isolates (dashed red line)

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