Fig. 2
From: X chromosome dosage and the genetic impact across human tissues
X chromosomal RNA expression. Unsupervised clustering of X chromosomal genes comparing 45,X (orangered), 46,XX (dark red), 46,XY (dark blue), and 47,XXY (light blue) in A blood, B fat, and C muscle. Dotplots demonstrating Log2 fold change of X chromosomal genes being differentially expressed between 45,X vs 46,XX or 47,XXY vs 46,XY or both and based on their X chromosome inactivation status (escape, inactive, variable) in blood, fat, and muscle (*p < 0.05) (D), and average group wise expression pattern of PAR1, escape and inactive genes on the X chromosome in blood, fat, and muscle (*p < 0.005, **p < 0.01, ***p < 0.001) (E). The red dashed lines visualize log 2FC at − 1, 0.58, and 1