Table 1 Full list of genes screened
From: Diagnostic yield of genetic screening in a diverse, community-ascertained cohort
Gene | Associated condition(s) |
|---|---|
APC | Colon polyps, colon cancer |
APOB | High cholesterol, coronary artery disease |
ATM | Breast cancer |
BMPR1A | Colon polyps, colon cancer |
BRCA1 | Breast, ovarian, and pancreatic cancer |
BRCA2 | Breast, ovarian, and pancreatic cancer |
BRIP1 | Breast and ovarian cancer |
CDH1 | Breast and stomach cancer |
CHEK2 | Breast and colon cancer |
EPCAM | Colon, endometrial, and ovarian cancer |
HOXB13 | Prostate cancer |
LDLR | High cholesterol, coronary artery disease |
MLH1 | Colon, endometrial, and ovarian cancer |
MSH2 | Colon, endometrial, and ovarian cancer |
MSH6 | Colon, endometrial, and ovarian cancer |
MUTYH | Colon polyps, colon cancer |
NTHL1 | Colon polyps, colon cancer |
PALB2 | Breast and ovarian cancer |
PMS2 | Colon, endometrial, and ovarian cancer |
PTEN | Colon polyps, colon cancer |
RAD51C | Ovarian cancer |
RAD51D | Ovarian cancer |
SMAD4 | Colon polyps, colon cancer |
STK11 | Colon polyps, colon cancer |
TP53 | Breast and many other cancers |