Fig. 2
Patient outcome. a Kaplan–Meier curves contrasting the two screening subpopulations (S: screened, N-S: non-screened) including all patients in the study and including only patients that belong to the three main clinical subgroups using overall survival as endpoint. b Univariate OS and DRFi hazard ratio with 95% confidence interval for screened patients in clinical subgroups/molecular subtypes when using non-screened patients as reference (ref). c Multivariate OS hazard ratio with confidence interval for patients in three clinical subgroups. Categories used as reference for each variable are marked in gray. Asterisks in b and c indicate failure of fulfilling the proportional hazards assumption for Cox regression (p < 0.05)