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Fig. 3 | Genome Medicine

Fig. 3

From: Location and condition based reconstruction of colon cancer microbiome from human RNA sequencing data

Fig. 3

Associations of microbiome profiles reconstructed from colon adenocarcinoma (COAD) with tumour properties. a Heatmaps of the q values of the association and correlation between the first six principal components (PCs) of COAD microbiome profiles (PCs in rows, clinical properties in columns). b Boxplot of PC2 coordinates by consensus molecular subtypes (CMS), highlighting the particular behaviour of CMS1 microbiome profiles. c Heatmap analogous to a that links the first six microbiome PCs of COAD samples and immune cell infiltration (relative quantification by CIBERSORTx). d Kaplan–Meier analysis of disease-free survival on patients stratified by high or low values of PC4. CIMP, CpG methylation phenotype; MSI, microsatellite instability; BMI, body mass index; NK, natural killer. Number of samples analysed in brackets

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