Fig. 5

Phylogeny of 458 19A ST320 genomes from different countries, and temporal trends of 19F ST271 and 19A ST320 in China. a Bayesian skyline plot of genetic diversity shows sharp expansion of 19A ST320 around 2001. The vertical axis shows the estimated effective population size at the corresponding time. The shaded blue areas on either side of the line represent 95% HPD confidence intervals. b The proportion of 19F ST271 and 19A ST320 in our collection every 2 years. c Reconstructed recombination-masked phylogeny 19A ST320 genome, consists of samples from this study (n = 175) and GPS (n = 283). One of the 19F ST320 isolates in this study SP65 was used as outgroup. The color strip represents the country from which the sample was isolated. Bold clades include isolates from both China and the other countries, supported by ultrafast bootstrap values of ≥ 89, with the values marked on the nodes