Table 1 Schizophrenia GWAS and rare coding variant genes in DEGs. Rare coding variants are listed in red. SP4 was in implicated in SCZ in both GWAS and exome sequencing studies
Gene | Log fold change | p-value | Expression in SCZ |
|---|---|---|---|
STAG1 |  − 0.65432192 | 0.000211006 | Downregulated |
ASH1L |  − 0.574034203 | 0.001639272 | Downregulated |
MSI2 |  − 0.628298006 | 0.002623759 | Downregulated |
FAM114A2 |  − 0.379608028 | 0.004309934 | Downregulated |
SP4 |  − 0.741815974 | 0.005321399 | Downregulated |
ZNF823 |  − 0.441175662 | 0.005530187 | Downregulated |
ZNF136 |  − 0.474551229 | 0.008610404 | Downregulated |
SF3B1 |  − 0.276285598 | 0.008889232 | Downregulated |
DCLK3 | 1.756895082 | 0.009724435 | Upregulated |
EIF2S3 | 0.29021066 | 0.010107875 | Upregulated |
ENOX1 |  − 0.885135386 | 0.012875532 | Downregulated |
MAD1L1 |  − 0.359021879 | 0.013981546 | Downregulated |
RB1CC1 |  − 0.485352017 | 0.016544659 | Downregulated |
BCL11B |  − 1.536911061 | 0.022580399 | Downregulated |
WSCD2 |  − 1.422044855 | 0.024713595 | Downregulated |
SLC39A8 | 0.909995356 | 0.03063367 | Upregulated |
EMX1 | 1.63706111 | 0.03109794 | Upregulated |
RERE |  − 0.765833586 | 0.031917862 | Downregulated |
HIST1H1E |  − 0.914444985 | 0.033835341 | Downregulated |
NEGR1 |  − 1.11617521 | 0.033886208 | Downregulated |
DCC | 1.286228948 | 0.039496096 | Upregulated |
PCDHA8 |  − 0.608954035 | 0.042243822 | Downregulated |
ANKRD12 |  − 0.560118184 | 0.046496813 | Downregulated |
HERC1 |  − 0.402594143 | 0.048675911 | Downregulated |