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Fig. 5 | Genome Medicine

Fig. 5

From: Impact of the SARS-CoV-2 nucleocapsid 203K/204R mutations on the inflammatory immune response in COVID-19 severity

Fig. 5

Immune cell composition predicted from transcriptome data and schematic summary. A The average proportion of immune cell types predicted from transcriptome data. B The proportion of neutrophils predicted from transcriptome data. Asterisks show significant difference (****p-values < 0.0001, paired two-sided t-test KR-vs-RG). C The neutrophil to lymphocyte ratio (NLR) predicted from transcriptome data. The proportion of lymphocyte corresponds to the sum of proportions of T cells, B cells, and NK cells. The p-values (** < 0.0062), calculated by paired two-sided t-test, show significant difference between KR and RG samples. D Schematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response

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Genome Medicine

ISSN: 1756-994X

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