Fig. 1
From: Ancestry-driven metabolite variation provides insights into disease states in admixed populations
Study design and results. Hispanic/Latino populations are descendants from African, European, and Native American ancestral populations. Joint (all-ancestry) and ancestry-specific admixture mapping was performed using genetic, metabolic, and clinical data from 3887 Hispanic/Latino individuals. Conditional admixture mapping analysis determined individual local ancestry regions. These local ancestry regions were fine-mapped using GWAS results from a previous study. Annotation and clinical phenotypes were obtained for significant variants from conditional admixture mapping analysis