Fig. 1

Outline of the study. a Schematic showing the method for reconstructing EPIs in each cell and tissue type. In total, we included 958 human samples from FANTOM5 project (Table S1), which can be further grouped into 439 different cell and tissue types (Table S2). b Analysis of the reconstructed EPIs showing their tissue specificity (i.e., comparing between brain and non-brain samples) and developmental stage (i.e., comparing between fetal, newborn and adult samples) specificity. c The EPIs reconstructed in the neural cell and tissue types were used to prioritize the associated genes of 17 different neurological disorders, psychiatric disorders, and behavioral-cognitive phenotypes by integrating with their GWAS summary statistics data