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Fig. 3 | Genome Medicine

Fig. 3

From: Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis

Fig. 3

Genome-wide genetic overlap and genetic correlation among irritable bowel syndrome (IBS), generalized anxiety disorder (GAD), major depression (MD) bipolar disorder (BIP), schizophrenia (SCZ), diverticular disease (DVD), inflammatory bowel disease (IBD), and Height (HGT). The numbers in colored Venn diagrams indicate the number of shared and phenotype-specific trait-influencing variants which account for 90% of heritability in thousands, and rg represents genome-wide genetic correlation. N.B. For GAD, MD, and DVD, the value of minimum AIC was negative — an indicator that the shared component may be smaller than shown in the figure model fit (MiXeR analysis)

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