Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence

Fig. 2

Differential expression analysis of A tumor clusters (subset of spots classified as a tumor in the clustering) from responders versus B tumor clusters from non-responders across all patients. C Volcano plot of the differential expression analysis showing the most differentially expressed genes in responders (red dots) and non-responders (blue dots), showing the upregulation of immune genes in responders relative to the upregulation of hepatocellular markers among non-responders. D Pathway enrichment analysis between responders (red dots) and non-responders (blue dots) reveals activation of immune-related pathways in responders’ tumors, while non-responders' tumors have activation of proliferation and metabolic pathways

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us