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Table 1 Measurements and cutoff values for classifying the examined Dobermanns into groups with normal or abnormal echocardiography and 24-h ECG (Holter) results. The cutoffs were based on the recommendations of Wess et al. [12]

From: Identification of novel genetic risk factors of dilated cardiomyopathy: from canine to human

Measurement

Normal

Abnormal

LVEDV/BSA (SMOD)

< 95 ml/m2

≥ 100 ml/m2

LVESV/BSA (SMOD)

< 55 ml/m2

≥ 60 ml/m2

LVIDd (M-mode)

< 46 mm (female)

≥ 46 mm (female)

< 48 mm (male)

≥ 48 mm (male)

LVIDs (M-mode)

< 36 mm (female and male)

≥ 36 mm (female and male)

24-h Holter monitoring

< 50 VPCs/24 h

≥ 300 VPCs/24 h or 50–300 VPCs/24 h in two subsequent records within 1 year

  1. BSA body surface area, LVEDV left ventricular end-diastolic volume, LVESV left ventricular end-systolic volume, LVIDd left ventricular internal diameter end diastole, LVIDs left ventricular internal diameter end-systole, SMOD Simpson’s method of disks, VPC ventricular premature complex