Fig. 5From: Integrated study of systemic and local airway transcriptomes in asthma reveals causal mediation of systemic effects by airway key driversAssociations between PBMC key drivers and asthma are causally mediated by nasal key drivers. PBMC key drivers and nasal key drivers associated with asthma were examined. Triangle edges summarize pairwise associations. Red arrows indicate significant causal mediation by nasal key drivers (FDR \(\le\) 0.05)Back to article page